The known genetic contributors to familial pancreatitis ... like cisplatin for increasing DNA damage. Germline mutations like those in ATM, and PALB2, for instance, identify individuals at risk ...

timing and frequency of germline and somatic testing for HRRm, and line of therapy where novel hormonal therapies and/or PARP ...

"It's known that germline structural variation also can contribute to the molecular profile of cancers," Creighton said. "Here we study the extent of its contribution." The researchers worked with ...