Mutations can be grouped into two main categories based on where they occur: somatic mutations and germ-line mutations ... of nucleotides are called gene-level mutations, because these mutations ...

"We were able to confirm that two previously suspected hereditary genes, PALB2 and ATM, are likely responsible for some hereditary HGSOC cases, and we also identified a new gene that may be linked ...

There is no single genetic blueprint for cancer. Instead, each individual cancer draws on a collection of acquired mutations that endow the cells ... earlier cancer onset if they carried predisposing ...

The genetic ... different germline genetic mutations had of developing cancer in both breasts, known as contralateral breast ...

The known genetic contributors to familial pancreatitis ... like cisplatin for increasing DNA damage. Germline mutations like those in ATM, and PALB2, for instance, identify individuals at risk ...

With delays in biomarker testing and treatment for metastatic castration-resistant prostate cancer, continued education is ...