The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to ...

We also found that tumor growth induces overly activated regulatory T (Treg) cells with their CTL suppressor function titratable along the PI3K-Akt-Foxo1 signaling pathway to overcome cancer immune ...

We have shown that tumors with HER2 amplification or PI3K mutation are selectively dependent for growth on the PI3K pathway and are sensitive to specific inhibitors of PI3K or AKT. Inhibition of PI3K ...

The results showed that cordycepin significantly inhibited growth factor signaling in multiple cell lines, particularly through the MEK/ERK and PI3K/AKT/mTOR pathways. This inhibition was observed ...

The study revealed that NAM activates CK1-mediated β-catenin signaling, while PN stimulates the AKT pathway, both of which are critical for MuSC proliferation and differentiation. Custom high ...