Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

In the latest PNAS paper 2, aneuploidy as the functional genetic basis of cancer passes both these tests in ways that should be of interest to biotechnologists of a variety of stripes. Of all the ...

Aneuploidy is frequent in cancer, but in vitro it triggers multiple cellular stresses and often delays proliferation. Through ...

Cancer cells have special adaptation mechanisms that allow them to proliferate despite changes in their genetic makeup.

However, aneuploidy in healthy cells was considered ... cells contained changes similar to ones seen in cancer cells. For example, one healthy woman had 70 cells with extra copies of chromosome ...

Chromosomal abnormalities occur in 0.1% to 0.2% of live births, and the most common clinically significant aneuploidy among live-born infants is Down syndrome (trisomy 21). Other sonographically ...

Sameer Raniga, MD, DNB; P.D. Desai, MD; Hetal Parikh, MD The most commonly studied soft markers of aneuploidy include a thickened nuchal fold, rhizomelic limb shortening, mild fetal pyelectasis ...