California-based nonprofit Arc Institute and Stanford University, in collaboration with NVIDIA, unveiled Evo 2 on Wednesday ...

Individuals who carry the breast cancer genes BRCA1 or BRCA2 are often unaware of the fact. That suggests that physicians need a new way to apply DNA-based screens to identify those at risk.

CRISPR technology has radically transformed genetic research, and at the forefront of this transformation is CRISPR screening ...

During the DNA damage response (DDR), repair proteins such as the E3 ubiquitin ligase BRCA1 accumulate at DNA ... evidence that SUMO and ubiquitin function together at DSBs to promote DNA repair.

Sensitivity to ionizing radiation is compelling evidence that BRCA1-and BRCA2-deficient cells are defective in repair of DSBs. As discussed above, 2 separate pathways play major roles in DSB repair in ...

A team of US scientists has developed a new foundation model that can sift through genetic code across biology's five ...

I underwent an oophorectomy at MD Anderson due to my BRCA1 gene mutation ... vital for repairing cell damage and ensuring proper cell function. However, this process is disrupted when a BRCA ...

"Around 40% of HGSOC has an inherited component and some of this is due to well-known genes like BRCA1 and BRCA2, for which testing is available," he said. "Our research set out to uncover new ...

For example the BRCA1 and BRCA2 genes that can contribute to breast cancer. Mutations in these genes account for approximately 10% of all inherited breast cancer cases detected. Scientists ...

Certain inherited gene mutations, like those in the BRCA1 and BRCA2 genes, can dramatically increase the likelihood of developing cancers such as breast and ovarian cancer. Conditions like Lynch ...