A University of Ottawa neuroscientist has led a Canadian research team to reveal important new insights into the activation dynamics of neural stem cells (NSCs). These are the stem cells that build ...

Lastly, in vitro knockout experiments revealed the necessity for both JPT2 and LSM12 for not only unlocking calcium signaling but also other NAADP-dependent cellular functions. When the researchers ...

New research reveals that brain cells use a muscle-like signaling mechanism to relay information over long distances.

and to calcium ionophores and phorbol esters, which in combination elicited a full 'T cell–activation' response but individually could be used to distinguish signaling pathways activated by ...

Scientists have discovered that neural stem cells (NSCs) receive constant feedback from their daughter cells, influencing whether they remain dormant or activate to form new neurons and glia.

"We also suspect that this enables this weak calcium signal to spread from cell to cell without disrupting other signaling calcium-dependent processes that are occurring simultaneously in these ...