Furthermore, how can BMV proteins that assemble with conformational specificity to form T=3 empty capsids adapt to form T=1 and pseudo-T=2 capsids around commensurate cargoes? Krol, M. A., et al., RNA ...

Researchers at the Max Planck Institute of Biophysics and Heidelberg University have observed largely intact HIV-1 capsids as ...

now show that one of the proteins in the head-to-tail connector of the phage particle can form a stopper that blocks the DNA from exiting the capsid. Tailed bacteriophages, including the Bacillus ...

The HIV-1 capsid is formed by a mesh of around 200 protein hexamers and pentamers, arranged similarly to a football. It is, however, not spherical, but shaped like a cone, with a narrow and a ...

To use the PP7 coat protein as a tag for imaging, Chao made a truncation that interfered with assembly of the capsid but still allowed the protein to dimerize and bind RNA. After the biochemical ...

Using this model, the researchers generated proteins with mutations that were ... worked well in identifying new sequences for the viral capsid of adeno-associated virus (AAV), a viral vector ...

The drug was named Science magazine’s 2024 “Breakthrough of the Year” for its remarkable efficacy and its innovation in targeting the capsid protein ... also provide a model for the ...

Together with the existing Vericheck ddPCR Empty-Full Capsid Kits for serotypes AAV5 and AAV9, the addition of the new kits for serotypes AAV2 and AAV8 extends the range’s suitability to approximately ...