Mammalian genomes are organized by multi-level folding, yet how this organization contributes to cell type-specific transcription remain unclear. We uncovered that the nuclear protein SATB1 ...

Chromatin immunoprecipitation (ChIP) is a technique for identifying and characterizing elements in protein-DNA interactions involved in gene regulation or chromatin organization. Microarray ...

Now, FMI researchers found that a component of a specific family of chromatin remodelers is important for placing nucleosomes in the right spots to keep certain areas of the DNA open. In this ...

Rice University’s Anna-Karin Gustavsson has been awarded a National Science Foundation (NSF) CAREER Award to advance her ...

This factor, which scientists previously found regulates chromatin organization, dropped in abundance as progenitors transformed into neutrophils, suggesting nuclear remodeling might kick off in its ...