Translocations generate novel chromosomes, but are often linked to disorders like infertility and cancer. How do these new chromosomes generate problems, and how are they detected? Translocations ...

Medically reviewed by Marla Anderson, MD Multiple myeloma is a rare type of blood cancer that starts in your plasma cells.

Chromosomal translocation fusion proteins contain a unique sequence at the junction of the fusion entities. The development of immunotherapies contingent on lymphocyte recognition of the junction ...

Professor Terry Rabbitts’ research is focussed on new strategies using intracellular antibodies and derivates for therapy aimed at hard-to-drug chromosomal translocation gene products. Our research is ...

A century after Down syndrome was first described, scientists discovered that the root cause of this disorder is a condition called trisomy 21. What strides in research have been made since then?

and represented the detection of chromosomal translocations in human cells, among other fabrications. In some cases, Chen indicated that gene therapy experiments were successful when in ...

Lucy Glade-Wright and Jonno Rodd say they have IVF to thank not only for their son Otis and his baby brother who will be born ...

We found that, contrary to popular belief at the time, a significant percentage of patients with CLL have chromosomal translocations — chromosomal abnormalities that occur when pieces of DNA are ...

In the case of oncogenic gene fusions, the hybrid mRNA is unique to the tumor cell. Attempts have been made to circumvent the problems of antisense oligonucleotides by developing highly target ...