Chromosomes carrying the mutation causing the fragile X [ fra (X) ] syndrome have been shown to have an unstable DNA sequence close to or within the fragile site. The length variation is located ...

Fragile X syndrome is caused by an expansion of CGG nucleotide repeats in the FMR1 gene at the end of the long arms of the X chromosome. To identify the mutation, researchers culture cells in media ...

Females (XX) carry twice as many X-linked genes on their sex chromosomes as males (XY). How do cells control gene expression to manage this potentially lethal dosage problem? A prime example of X ...

“The mutation that causes FXS can ... “Because females have two X chromosomes, and usually only one of them is affected by ...

For example, mutations in the FMR1 gene on the X chromosome cause fragile X syndrome, a condition associated with intellectual disability. Turner syndrome, a condition where females are born with only ...

Previous research has hinted that the X chromosome is vital to brain health. Mutations in the X chromosome may cause intellectual disability, and women born with just one X chromosome (a diagnosis ...