Cyclin-dependent kinases (CDKs) are protein kinases involved in critical cellular processes, such as cell cycle or transcription, whose activity requires association with specific cyclin subunits.

CR8 inhibits all cyclin-dependent kinases (CDKs), which have multiple roles in tumor development, but it also degrades the protein cyclin K, which promotes cancer signaling pathways. Previous ...

A "pocket" on the protein cyclin B is responsible for ensuring ... The reason for this lies in the cyclins' cooperation with a kinase. Kinases are responsible for phosphorylating amino acids ...