But, perhaps a more underrated pick for Spider-Man's greatest foe is the wonderfully complex Doctor Otto Octavius, aka Doctor Octopus ... Raimi's iconic film Spider-Man 2 and Insomniac Games ...

Ultimate Spider-Man #5 teases a battle between a young Doc Ock and the inexperienced Spidey, paving the way for exciting new dynamics. Doctor Octopus' new ... Raimi's Spider-Man 2 and Marvel's ...