Scheduled Feeding improved sleep/wake rhythms in the Fmr1 KO mutants.

Variation in the number of CGG repeats in the FMR1 gene at the bottom of the X chromosome can lead to increased levels of mRNA or decreased levels of protein—both conditions that cause disease.

What causes it? “Fragile X syndrome is caused by a change in the FMR1 gene, and the FMR1 gene is located on the X chromosome,” explains Richardson. “This abnormal gene, which can be passed ...

The FREE methylation test has been closely related to FMR1 protein expression and identified fragile X syndrome (FXS)-affected males and females with 100% specificity in our small study (75 male ...

Diagnosis: Fragile X-associated tremor/ataxia syndrome (FXTAS) resulting from a premutation (CGG repeat) expansion of the FMR1 gene. Management: Explanation of the genetic ramifications of ...

A recent theory about the basis for fragile ... fragile X syndrome (FXS), an inherited form of mental retardation and the predominant monogenetic cause of autism. The study is also a genetic ...

Neuroscience specialist Harmony Biosciences has agreed to acquire Zynerba, adding its cannabidiol (CBD) gel product Zygel for Fragile X syndrome ... a mutation in the FMR1 gene.