Insulin resistance is concomitant with type 2 diabetes, obesity, hypertension, and other features of the metabolic syndrome. Because insulin resistance is associated with cardiovascular disease ...
involving the stabilization of the insulin molecule to make it bioavailable in the dry powder form. It was the first insulin product that did not need to be injected, so when it was approved in ...
Understanding the molecular mechanisms of insulin resistance remains a major medical challenge of the twenty-first century. Over the last half-century, many hypotheses have been proposed to ...
It is obtained by inverting of the lysine at position 28 and the proline at position 29 on the ß-chain of the insulin molecule: it confers a conformational change that results in a quick ...
Based on the molecular mimicry hypothesis, the team identified 17 microbialpeptides very similar to insulin B:9-23. Testing them in immune cells obtained from type 1 diabetes patients, they identified ...
Bengaluru: ‘Smart’ insulin that responds to rise and fall of blood sugar levels in real-time promises to revolutionise the ...
They found one molecule that had a large effect on FLP-7: a form of insulin known as INS-7. In humans, insulin is most known ...
Women who have gestational diabetes have increased risk of type 2 diabetes in the years after delivery. Those who go on to develop the chronic disease fall into three "clusters," each with a distinct ...
Dr Destecroix, described the molecule could be the "holy grail" of insulin and said he hoped the sale will offer ground-breaking treatment for diabetics. He said: "It wasn't a surprise when the ...