智通财经APP获悉，1月15日，中国国家药监局药品审评中心(CDE)官网最新公示，阿斯利康(AZN.US)1类新药AZD0022获得临床试验默示许可，拟开发治疗携带KRAS ...

经济观察网讯 1月15日，中国国家药监局药品审评中心（CDE）官网最新公示，阿斯利康1类新药AZD0022获得临床试验默示许可，拟开发治疗携带KRAS G12D ...

Quanta Therapeutics Inc. has identified new pyrimidine-based GTPase KRAS G12D and G12V mutant inhibitors potentially useful for the treatment of cancer.

Merck Sharp & Dohme LLC patents report the development of proteolysis targeting chimera (PROTAC) compounds comprising an E3 ubiquitin ligase (Von Hippel-Lindau disease tumor suppressor [VHL] ligands) ...

SIL-204 inhibits key oncogenic KRAS mutations, including G12D, G12V, G12R, Q61H, and G13D. Intratumoral administration of SIL-204 microparticles reduced tumor cell numbers by ~3-fold, tumor area ...