Fibrosis is characterized by the excessive ... the secreted enzymes lysyl oxidase-like 2 (LOXL2) and autotaxin (ATX). Currently, the company’s portfolio includes PAT-1251, a phase 2-ready ...

Scientists are looking at a range of different drug classes, such as lysyl oxidase (LOX ... the lung scarring disease idiopathic pulmonary fibrosis (IPF). But other companies continue to see ...

Our chemical probe – FibroDetect Probe – addresses this unmet need for innovative diagnostic tools and interventions by targeting the hallmark of fibrotic ECM pathophysiology: excessive collagen ...