and dephosphorylation (catalyzed by protein phosphatases). Protein kinases mediate most of the signal transduction events in cells by phosphorylation of specific substrates - modifying their activity, ...

In immune cells, scaffold proteins have an important role in the regulation of mitogen-activated protein kinase activation ... modelling predicts that when phosphatase activity is high, scaffold ...

MK-STYX is a novel protein included in the dual specificity mitogen-activated protein kinase phosphatase class that lacks the essential nucleophilic cysteine required for phosphatase activity.