or G-protein coupled receptors (GPCRs), in stimulation of mitogen activated protein kinase (MAPK) cascades. Rather, several distinct signaling mechanisms appear to contribute to GPCR-mediated MAPK ...

Figure 2: Mitogen-activated protein kinase scaffold proteins in immune ... an important role in facilitating the activation of the cascade, as in the absence of scaffold proteins kinases have ...

A new study gives hope for improved treatment of prostate cancer, the second most diagnosed cancer among men worldwide.

The emergence of pseudokinases and pseudophosphatases has made phosphorylation cascades even more complicated. My lab focuses on various functional characteristics of the pseudophosphatase map kinase ...

Blenis, "ras mediates nerve growth factor receptor modulation of three signal- transducing protein kinases: MAP kinase, Raf-1, and RSK," Cell ... "This paper shows that RAS functions to regulate a ...