Kinases, enzymes that phosphorylate proteins, generally control the amplitude of a signal response, whereas phosphatases, enzymes that dephopshorylate proteins, are thought to be important for ...

Protein phosphorylation is a covalent post ... Tyrosine kinases and tyrosine phosphatases, as well as SH2 and PTB domains, have been investigated in some detail over the past several years.

A new study published in Advanced Science has revealed how curcumin, a bioactive compound found in Curcuma aromatica (Yujin), ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

Figure 1: Contribution of wild-type (WT), Ptpn11-mutant or Fgfr1-mutant ES cells to the developing E10.5 embryo. Figure 4: Development of both the limb buds and the branchial arches is impaired in ...

A new study published in Advanced Science has revealed how curcumin, a bioactive compound found in Curcuma aromatica (Yujin), ...

The acquisition bolsters Boehringer's immuno-oncology pipeline with Nerio's new PTPN2/N1 [protein tyrosine phosphatase ...

MD-18 is a new peptide targeting protein-tyrosine phosphatase 1B (PTP1B) that is intended to become a key player in glucose ...

Shenzhen Zhongge Biotechnology Co. Ltd. has disclosed tyrosine-protein phosphatase non-receptor type 2 (PTPN2; TCPTP) inhibitors reported to be useful for the treatment of cancer.

Suzhou Genhouse Bio Co. Ltd. has disclosed tyrosine-protein phosphatase non-receptor type 11 (PTPN11; PTP-2C; SHP-2) inhibitors reported to be useful for the treatment of cancer, Noonan syndrome and ...