Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

The acquisition bolsters Boehringer's immuno-oncology pipeline with Nerio's new PTPN2/N1 [protein tyrosine phosphatase ...

Adrenomedullin (ADM) inhibits endothelial insulin signaling, contributing to obesity-associated insulin resistance, according ...

A new study published in Advanced Science has revealed how curcumin, a bioactive compound found in Curcuma aromatica (Yujin), ...

Protein tyrosine kinases and protein tyrosine phosphatases coordinate to maintain a protein phospohorylation balance required for normal cell function. If this balance is disrupted, the outcome may be ...

Protein phosphorylation is a covalent post ... Tyrosine kinases and tyrosine phosphatases, as well as SH2 and PTB domains, have been investigated in some detail over the past several years.

Figure 1: Contribution of wild-type (WT), Ptpn11-mutant or Fgfr1-mutant ES cells to the developing E10.5 embryo. Figure 4: Development of both the limb buds and the branchial arches is impaired in ...

Shenzhen Zhongge Biotechnology Co. Ltd. has disclosed tyrosine-protein phosphatase non-receptor type 2 (PTPN2; TCPTP) inhibitors reported to be useful for the treatment of cancer.

Suzhou Genhouse Bio Co. Ltd. has disclosed tyrosine-protein phosphatase non-receptor type 11 (PTPN11; PTP-2C; SHP-2) inhibitors reported to be useful for the treatment of cancer, Noonan syndrome and ...

The most often studied kinases are protein kinases, which are generally subdivided into tyrosine, and serine/threonine-directed ... Cell lysates are prepared using M-Per lysis buffer with protease and ...