Researchers from Morphic Therapeutic Inc. and affiliated organizations published data from a study that aimed to assess the potential of using arginylglycylaspartic acid (RGD) integrins for the ...

Both wild-type IGFBP-2 and HBD-mutant IGFBP-2 contain the RGD sequence that allows binding with α5β1 integrin receptors. It has been shown that α5β1 integrin receptor activation leads to FAK ...

OcuTerra Therapeutics has reported that its Phase II DR:EAM clinical trial of selective RGD integrin inhibitor nesvategrast (OTT166) eye drops for patients with diabetic retinopathy (DR ...

The decision affects THR-687, a pan RGD integrin antagonist for the treatment of diabetic macular oedema (DME), and leaves Oxurion with a single clinical-stage candidate – plasma kallikrein ...

KS1767 cells were detached with cold EDTA and re-suspended in MEM containing 1% BSA. αv integrin-binding RGD-4C phage were used as defined ligands. The cell suspension was incubated with RGD-4C ...