Researchers from Morphic Therapeutic Inc. and affiliated organizations published data from a study that aimed to assess the potential of using arginylglycylaspartic acid (RGD) integrins for the ...

Both wild-type IGFBP-2 and HBD-mutant IGFBP-2 contain the RGD sequence that allows binding with α5β1 integrin receptors. It has been shown that α5β1 integrin receptor activation leads to FAK ...

The decision affects THR-687, a pan RGD integrin antagonist for the treatment of diabetic macular oedema (DME), and leaves Oxurion with a single clinical-stage candidate – plasma kallikrein ...

OcuTerra Therapeutics has reported that its Phase II DR:EAM clinical trial of selective RGD integrin inhibitor nesvategrast (OTT166) eye drops for patients with diabetic retinopathy (DR ...

KS1767 cells were detached with cold EDTA and re-suspended in MEM containing 1% BSA. αv integrin-binding RGD-4C phage were used as defined ligands. The cell suspension was incubated with RGD-4C ...