Diabetes can wreak havoc on the vasculature, leading to renal failure, blindness and cardiovascular disease. Such conditions are ultimately the result of reduced insulin production or insulin ...

The Bristol research initially focused on revealing underlying molecular mechanisms based on the glomerular podocyte, the central cell of the kidney filtration barrier. In 2002, the team led by ...

Steroid-resistant nephrotic syndrome (SRNS) is a devastating disease affecting both adults and children resulting from the breakdown of the kidney filtration barrier. It usually leads to end-stage ...

End-stage renal disease (ESRD) is defined as severe irreversible kidney damage, measured by the level of proteinuria and a reduction in the glomerular filtration rate to ˂15 ml/min/1.73 m2 ...

This often happens when kidney diseases damage the kidney’s filtration barrier, which is there to keep larger molecules like fats out of your urine. When this barrier is damaged, fats can leak ...

Nakamura shares "During our analysis of renal gene expression profiles ... therapeutic breakthroughs in treating glomerular filtration barrier dysfunctions, notably proteinuria.