How are induced pluripotent stem (iPS) cells different from embryonic stem (ES) cells? What can we use iPS cells for? ES cells were originally derived from the inner cell mass (ICM) or epiblast of ...

Somatic stem cells are present in many fetal and post-natal tissues. Somatic stem cells are also capable of self-renewal and, with appropriate signals, differentiate into various cell types from ...

In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells ...

New research shows persistent DNA lesions in stem cells contribute to mutations, with links to blood cancers and external ...

Research Interests: Somatic Stem Cells and Aging, Genetic Mechanisms of Stem Cell Maintenance, Therapeutic Approaches to Tissue Rejuvenation, Mouse Models of Hair Graying, Melanocyte Stem Cells and ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade ...

Since 2000, the International Space Station has brought together 280 astronauts from around the world in numerous flight operations and celestial research. However, these specialized scientists do ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Therefore the stem-like cells are likely to exhibit a distinct gene expression program that is compatible ... single-cell transcriptomics data to reduce cellular heterogeneity in tumors. These ...

Scientists at the Wellcome Sanger Institute uncovered DNA damage that can persist for years, evading repair mechanisms and increasing mutation risks. This phenomenon provides new insights into cancer ...

Since stem cells have the ability to turn into various other types of cells they can be useful for treating and understanding disease. Researchers can use stem cells in laboratories to test new ...