If the leader is long, it may contain regulatory sequences, including binding sites for proteins, that can affect the stability of the mRNA or the efficiency of its translation. Translation Begins ...

The function of these multiple mRNA export factors is not yet certain. Yra1, other mRNA-binding proteins, the cap-binding proteins Cbp20 and Cbp80, and the poly(A) + RNA-binding protein Pab1 may ...

In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.

Those strands of mRNA penetrate certain human cells ... produce antibodies that will block the actual virus' spike proteins from binding to people's cells and infecting them.

A new experimental vaccine could offer protection not only against many variants of SARS-CoV-2, but also other sarbecoviruses that could spill over from animals to humans.

Despite this protection, mRNA’s defense is short-lived, with an average half-life of just seven hours. The degradation ...

In a process called deadenylation, the target mRNA is recruited by RNA-binding proteins to the protein complex CCR4-NOT, ...

A recent study reveals the pivotal role of tristetraprolin (TTP), an RNA-binding protein, in regulating inflammatory responses in basophils, immune cells central to allergic reactions. The research ...

Researchers developing Australia’s first mRNA Covid vaccine say they ... aims to tackle the problem by encoding the proteins on the surface of the receptor-binding domain — the tip of the ...