The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But where does translation take place within a cell?
In this review of RNA therapies, we paint an overview of what’s going on in a field that is addressing a number of diseases.
What instructions prevent premature mRNA translation before fertilization? In the 1960s and 1970s, scientists asked this question and came up with two possible answers. In 1966, Alexander Spirin ...
During the oocyte-to-embryo transition (OET), the length of the mRNA poly(A) tail is closely linked to its translational ...
However, the therapeutic effectiveness is limited by the poor translation uptake of naked mRNA. To circumvent this challenge, researchers from VIB, VUB, Ghent University, and eTheRNA ...
(Image: ttsz/iStock via Getty Images Plus) The Role of mRNA in Gene Expression Messenger RNA is an essential component of the gene expression process, which involves the conversion of genetic ...
Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...