Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...
Glial cells come in many forms, but three major types are currently recognized: astrocytes, oligodendrocytes and microglia. The first are primarily involved in creating the blood-brain barrier and ...
A potential cause-and-effect relationship implicating astrocytes in the neurotoxicity observed in HD was noted following the observation in a neuron–glial co-culture that wild-type glial cells ...
Astrocytes are star-shaped glial cells in the central nervous system that support neuronal function, maintain the blood-brain barrier, and contribute to brain repair and homeostasis.
The increasing implication of glial cells in neurodegenerative diseases makes them an appealing addition to iPSC-based model systems for investigating disease mechanisms. Over the last decade, Dr.
Moving towards function, our recent endeavors focused on decoding the cellular and functional diversity of astrocytes in the adult brain. In both cases, we made fundamental observations about the ...
as well as in “glial” cells called astrocytes and oligodendrocytes, which can support neural signaling by controlling neurotransmitter levels and electrically insulating nerve fibers.
Learn about our Editorial Policies. Led by postdoctoral researcher Benjamin Clayton, Tesar’s team built and validated their new discovery platform with sequencing and cellular technologies, examining ...
Cell 2008), applying these principles to astrocyte populations in the adult brain has remained a challenge because ... Two critical intersection points for the mechanisms underlying glial development ...