Maintenance of cerebral blood vessel integrity and regulation of cerebral blood flow ensure proper brain function. The adult human brain represents only a small portion of the body mass, yet about a ...

It is important to identify infants of affected women as high-risk infants. Scrutinize the maternal history and, when possible, determine the specific EDS type of the mother or affected family ...

Aortic dissection, one of the best studied arterial dissection types, is associated with dysfunction of interlinked TGF-β signaling pathways, and disruption of extracellular matrix (ECM) structure, ...

Chromosome 7 COL1A2 (collagen, type 2, alpha 2) Same Chromosome 9 COL5A1 (collagen, type 5 alpha 1) Same Chromosome 2 COL5A2 (collagen, type 5, alpha 2) Same ...

familial acute respiratory distress syndrome, ANLN-related, dog (MONDO:1012930) neuromuscular channelopathy, KCNG1-related, cattle (MONDO:1012911) progressive retinal atrophy, FAM161A-related, dog ...

Epigenetics is a wide-encompassing term that is best described by Riggs and Porter13 as mitotically or meiotically heritable changes to genetic function not attributable to gene sequence. The field ...

Background The Ehlers-Danlos syndromes (EDS) are heritable disorders of connective tissue (HDCT), reclassified in the 2017 nosology into 13 subtypes. The genetic basis for hypermobile Ehlers-Danlos ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Esophagitis is a frequent, but at the ...

Could nanotechnology improve exercise performance? Evidence from animal studies Lima, M.R. Moreira, B.J. Bertuzzi, R. Lima-Silva, A.E.