For most proteins, these two opposing processes are dynamically balanced during the cell cycle, holding each protein ... during normal cell cycles. In a control experiment, when the proteasome ...

For example, during S phase, protein 'machines' generate the replication ... The simplest cell cycle reveals the essential minimum of cell-cycle control. Unfortunately, differentiated cells ...

Learn more about the high-purity GMP-grade human activin A / INHBA protein, designed for therapeutic and research ...

The ICIT mechanism's ability to control protein translation at the single-cell level also offers a transformative approach to the treatment of cancers and other tissue-specific diseases.

There are many molecules with therapeutic potential, but it can be a challenge to deliver them to the right places at the ...

Ubiquitin-specific protease 7 (USP7) is involved in DNA repair and cell cycle progression and, due to its control over the ubiquitination of key proteins, may impact oncogenes like MDM2 and c-Myc, as ...

The goal of our research is to provide a detailed mechanistic understanding of mitochondrial quality control proteins in order to exploit ... Visualizing the ATPase cycle in a protein disaggregating ...

When Xiao Wang applied to faculty jobs, many of the institutions where she interviewed thought her research proposal - to ...

More information: Jun Zhang et al, Modular Photoswitchable Molecular Glues for Chemo‐Optogenetic Control of Protein Function in Living Cells, Angewandte Chemie International Edition (2025). DOI ...

They found that Talin-1, a protein primarily known for ... forces is required for its capacity to control gene expression. This discovery in basic cell biology has important medical implications ...