Chromatin organization strengthens DNA for mechanically stressful processes like mitosis, helps protect DNA from damage and is important in the control of gene expression and DNA replication.

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer ...

Short-chain fatty acids (SCFAs) like propionate and butyrate are critical byproducts of dietary fiber digestion. These ...

New research from the Center for Physical Genomics and Engineering uncovers how 3D genome structures generate cellular memories, paving the way for advances in medicine and longevity through cellular ...

Major changes in gene expression underlie changes in cell state, including cell growth and a stress-resistant state called quiescence. Our scientists study how the organization of our chromatin - the ...

A new research perspective was published in Aging (listed by MEDLINE/PubMed as “Aging (Albany NY)” and “Aging-US” by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled “Nuclear lipid ...

Since 2014, she leads her own research team in Weill Cornell Medicine in New York studying the critical interplay between TFs, 3D chromatin organization and transcription during cell cycle or cell ...

Centromeres play a crucial role in cell division, with CENH3 guiding retrotransposon Tal1 integration, revealing insights ...

Given the central role of the kidney in regulating BP, we hypothesized that chromatin-accessible regions in renal tissue would be enriched for BP-associated single nucleotide polymorphisms. We ...

The ALS Association is excited to announce the ALS Nexus 2025 conference, taking place August 11-14 at the Gaylord Texan Resort & Convention Center in Grapevine, Texas, just outside of Dallas.