The Great Seal of the Realm is the chief seal of the Crown, used to show the monarch's approval of important State documents. In today's constitutional monarchy, the Sovereign acts on the advice of ...

The Food and Drug Administration (FDA) has expanded its approval of a ketamine-derived nasal spray, Spravato (esketamine), as a standalone therapy for adults with treatment-resistant depression.

The FDA’s latest approval of the nasal spray Spravato (esketamine) CIII marks a major shift in how major depressive disorder is managed, allowing people who have tried at least two oral ...