Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

In my work as a cancer researcher, I study the underlying mechanisms of how tumors develop and resist treatment. By ...

Clinical research suggests that combining a novel agent called navtemadlin with DNA-damaging chemotherapy for the treatment of glioblastoma, a form of brain cancer, could increase efficacy.

CMRI researchers discovered that DNA repair pathways control how cancer cells die after radiotherapy. Blocking a key repair ...

Stanford Medicine researchers sifted through thousands of single nucleotide mutations in DNA to identify fewer than 400 that are functionally associated with inherited cancer risk.

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Preclinical studies have shown their potential to reduce inflammation and modulate immune responses in diseases like rheumatoid arthritis and lupus.

Results of a study led by the Vall d'Hebron Institute of Oncology (VHIO) support the feasibility of using RAD51 testing to ...

Drinking alcohol if you have a large belly or diabetes more than doubles the risk of serious liver damage, while having high blood pressure and drinking nearly doubles the risk, a new study found.

This DNA damage leads to uncontrollable growth of tissue instead of healthy, normal tissue growth. This abnormal tissue growth is cancer. The four pathways through which alcohol can lead to cancer ...