Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, providing insights into its DNA recognition and cleavage mechanisms.

Recent research has focused on optimizing cationic polymerization mechanisms and developing effective catalytic systems to enhance the efficiency and quality of the resulting polymers. The studies ...

Department of Chemistry, Lomonosov Moscow State University, Leninskie Gory, Bldg. 1, Moscow 119991, Russia ...

These mechanisms are just beginning to ... including continued semi-conservative replication, TLS polymerization and recombination-dependent DNA repair, ensures continuation of DNA replication.

DNA damage-induced immune stimulation occurs by a variety of mechanisms including by the cGAS/STING pathway, STAT1 and downstream TRAIL pathway activation, and direct immune cell activation. Whether ...

A study published in Nature Communications and conducted by researchers from the Institute of Physics of the Chinese Academy of Sciences revealed new details about the CRISPR-Cas5-HNH/Cascade complex, ...

Self-adjuvant nanomaterials can enhance the immunogenicity of DNA vaccines through various mechanisms, including (1) Improved antigen delivery ... such as high transfection efficiency and cationic ...

How ECs are still able to migrate after the inhibition of actin polymerization was unclear. As our current study demonstrates a role of water inflow and hydrostatic pressure as another mechanism of ...

This study convincingly shows that aquaporins play a key role in blood vessel formation during zebrafish development. In particular, the paper implicates hydrostatic pressure and water flow as ...

Post-polymerization modification of incorporated monomer units focus on two types of reaction. One is the removal of protecting groups where monomers with the desired functionality are incompatible ...

EaStCHEM, School of Chemistry, University of St. Andrews, North Haugh, St. Andrews KY169ST, U.K.

The Clean Development Mechanism (CDM), defined in Article 12 of the Protocol, allows a country with an emission-reduction or emission-limitation commitment under the Kyoto Protocol (Annex B Party) to ...