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Neuron丨为什么熟能生巧?多巴胺通过D1受体强化学习与记忆
将D1R表达的纹状体神经元中的D1R光激活与皮质神经记录相结合 作者将两种腺相关病毒(AAV)注入D1-Cre小鼠的背内侧纹状体。第一种病毒(pAAV-CAG-DIO-M-P2A-mScarlet)在D1表达神经元中选择性表达M蛋白,第二种逆行性病毒(pGP-AAVrg-syn-jGCaMP8s-WPRE)被皮质-纹状体投射 ...
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