Such models learn on a large collection of molecular structures and produce novel compounds ... We use this set to assess how well the model can generate previously unobserved scaffolds. Besides ...

The identical cultures used for metabolomics analysis were also used for RNA isolation and quantitative real-time RT-PCR (RT-qPCR) analysis of gene expression. RT-qPCR analysis was performed as ...

On February 3 in Molecular Plant, they report that this ... the team noticed that SUSIBA2 plants also release significantly more ethanol. Adding ethanol to the soil surrounding rice plants reduced ...

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They were the world's first supermodels, after all. But if you’re wondering how to become a model nowadays, a lot has changed since the ’90s—not least the introduction of the internet and ...

AI molecular design tool for de novo design, scaffold hopping, R-group replacement, linker design and molecule optimization.

This valuable study reports on the critical role of ANKRD5 (ANKEF1) in sperm motility and male fertility. However, the supporting data remain incomplete. This work will be of interest to biomedical ...

Torsional stress in chromatin plays a fundamental role in cellular functions, influencing key processes such as transcription, replication, and chromatin organization. Transcription and other ...

A multidimensional study of the clinical, histological and molecular features of these subtypes is lacking. Design Two large cohorts of patients were recruited in an international, observational ...