To answer this question, the authors used a combination of in vivo and ex vivo experiments in mice to demonstrate ligand-independent activation of Notch1 by circulation induced-mechanical stress and ...

Thrombotic complications are the second leading cause of death among oncology patients worldwide. Enhanced thrombogenesis has multiple origins and may result from a deregulation of megakaryocyte ...

One gene that showed up only in the iAssembloid screen is glycogen synthase kinase 3b. The GSK3b enzyme phosphorylates tau and frequently has been linked to Alzheimer’s and other neurodegenerative ...