One gene that showed up only in the iAssembloid screen is glycogen synthase kinase 3b. The GSK3b enzyme phosphorylates tau and frequently has been linked to Alzheimer’s and other neurodegenerative ...

ARHGEF3 also binds the mammalian target of rapamycin complex 2 (mTORC2) and subsequently inhibits mTORC2 and Akt. In vivo investigation has also indicated the communication between ARHGEF3 and ...

Recent studies demonstrate that in NK cells, conditionally disrupting the formation of mTORC1 or mTOR complex 2 (mTORC2) alters their development significantly. Transcriptomic profiling of NK cells at ...