All biological function is dependent on how different proteins interact with each other. Protein-protein interactions ...

This content introduces the physiological and pathological importance of protein kinases, kinase inhibitors approved for ...

Clinical research suggests that combining a novel agent called navtemadlin with DNA-damaging chemotherapy for the treatment of glioblastoma, a form of brain cancer, could increase efficacy.

Researchers have discovered how a particular protein affects the growth and spread of colon ... nasopharyngeal cancers and melanoma, DUSP6’s inhibition of ERK1/2 activation acts as a tumor ...

Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

The new study adds to growing evidence that measuring activated proteins is key to cancer therapy selection. Golden, CO, Feb.