This study provides a comprehensive comparison of the cardiovascular safety profiles of various Tyrosine Kinase Inhibitors (TKIs) used in the treatment of Non-Small Cell Lung Cancer (NSCLC). Our ...

Your body produces the enzyme creatine kinase (CK) or creatine phosphokinase to keep your muscles functioning properly. Healthcare providers use the CK test to check levels of this protein in your ...

Panelists discuss how the Bayesian network meta-analysis showed which Janus kinase (JAK) inhibitors were most effective in ...

This study presents fundamental findings that could redefine the specificity and mechanism of action of the well-studied Ser/Thr kinase IKK2 (a subunit of inhibitor of nuclear factor kappa-B kinase ...

Two sphingosine kinase isoforms, sphingosine kinase 1 (SPHK1) and sphingosine kinase 2 (SPHK2), synthesize S1P by phosphorylating sphingosine. While SPHK1 is a cytoplasmic kinase, SPHK2 is localized ...

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase first identified in a chromosomal translocation associated with some anaplastic large cell lymphomas (ALCL), a subset of T-cell non ...

The mechanistic target of rapamycin (mTOR) is a serine/threonine kinase whose activity contributes to leukemia proliferation and survival. Compounds targeting the mTOR active site inhibit ...

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No significant difference in the risk for MACE was observed between patients with IBD receiving JAK vs TNF inhibitors.

The best network switch will be a necessity for anyone looking to add more wired connections and gain greater network speeds. One of the biggest issues we've found with even the best routers and ...

The US Food and Drug Administration (FDA) has approved Romvimza (vimseltinib), from Deciphera Pharmaceuticals, a kinase ...

CSPC Megalith Biopharmaceutical has entered into a license agreement with Radiance Biopharma for the development and ...