New research published in Nature Communications reveals how cancer cells are altered by their surroundings, enabling them to ...

The glucoregulatory functions of pancreatic islets are affected by their surrounding niche and spatial organization. Here, bioengineered stem-cell derived islet niches use bioprinting-based ...

Scientists have discovered a new way to predict which tumours will become aggressive before they metastasise and spread ...

Scientists have discovered a new way to predict which tumours will become aggressive before they metastasise and spread around the body. New research, published in Nature Communications, reveals how ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

Connective tissue diseases are a heterogeneous group of autoimmune disorders that affect any of the body's connective tissues. These disorders can be inherited or acquired, and can present with a ...

Following this, the sections were treated with an acidic dye solution to stain collagen fibers. The Masson staining procedure allowed for the differentiation of collagen deposition from other tissue ...

Increasing tissue rigidity drives tumor invasion and malignancy and correlates with poor patient survival 1,2. A malignancy with a well-known link to overproduction of ECM components is hepatocellular ...