Metoprolol tartrate and metoprolol succinate are two forms of the same drug used to lower blood pressure and normalize the heart rate. Metoprolol is a type of beta-blocker generally prescribed to ...

A significant area of study involves succinate dehydrogenase inhibitors (SDHIs), which have shown promise in combating various fungal pathogens. These compounds are designed to target specific ...

Mechanistically, Acod1 suppressed osteoclast differentiation by inhibiting succinate dehydrogenase-dependent production of reactive oxygen species and Hif1α-mediated induction of aerobic glycolysis.

Sirtuins, identified as (NAD +)- dependent class III histone deacetylases, engage in a spectrum of biological functions, encompassing DNA damage repair, oxidative stress, immune modulation, ...

Yu-Ying He’s team screened multiple compounds and discovered vitamin E succinate as a potential degrader of FTO. “Unlike some of the other small inhibitors, VES has a well-characterized safety ...

Macrophages exist in most tissues of the body, where they perform various functions at the same time equilibrating with other cells to maintain immune responses in numerous diseases including cancer.

mail.nih.gov Objective Aldehyde dehydrogenase 2 (ALDH2), a key enzyme to detoxify acetaldehyde in the liver ... In vitro treatment with acetaldehyde inhibits production of cytokine proteins without ...

(Photo Credit: E+/Getty Images) The lactate dehydrogenase (LDH) test looks for signs of damage to your body’s tissues. Cars need gas or electricity to go. Your cells need an enzyme (proteins ...

These include sleep aids and allergy drugs that contain antihistamines, such as: diphenhydramine (Benadryl) doxylamine succinate (Nyquil) While diphenhydramine and doxylamine succinate are ...

On a population level, the effects of PPI are more prominent than the effects of antibiotics or other commonly used drugs. Proton pump inhibitors (PPI) use is associated with increased risk of enteric ...

The active metabolite of leflunomide, A77 1726, at low, therapeutically applicable doses, reversibly inhibits dihydroorotate dehydrogenase (DHODH), the rate limiting step in the de novo synthesis of ...