In the present experiments the effects on insulin secretion of theophylline, a methyl xanthine derivative which inhibits cyclic nucleotide phosphodiesterase 6 and increases the intracellular ...

School of Life Sciences, Fudan University, Shanghai, China International Human Phenome Institute (Shanghai), Shanghai, China Department of Endocrinology and Metabolism, Huashan Hospital, Fudan ...

The authors identified new target elements for prostaglandin E2 (PGE2) through which insulin release can be regulated in pancreatic beta cells under physiological conditions. In vitro extracellular ...

Zealand’s CEO Adam Steensberg said that the company is “exactly where it wants to be” in terms of its partnering and ...

Does aspartame increase heart disease risk? A new study in mice suggests a link, but experts caution against jumping to ...

Glucagon-like peptide-1 receptor agonists (GLP-1RAs), originally developed for treating diabetes, work by stimulating insulin secretion and suppressing glucagon release, thereby helping regulate blood ...

Insulin overdose symptoms can include confusion, fatigue, irritability, shaking, and other signs of low blood sugar (hypoglycemia). If you accidentally take too much or your blood sugar is low for ...

Lissencephaly is a severe neurodevelopmental disease often caused by mutations in the Dcx gene. Using a human cellular model of lissencephaly, the authors report that DCX restricts neuronal ...

A recent study published in Nature Microbiology reveals that consuming broccoli extract can significantly reduce fasting ...

The Clean Development Mechanism (CDM), defined in Article 12 of the Protocol, allows a country with an emission-reduction or emission-limitation commitment under the Kyoto Protocol (Annex B Party) to ...

Li, Y. and Zhou, B. (2025) Research Progress on the Relationship between Dynapenic Obesity and Type 2 Diabetes. Journal of Biosciences and Medicines, 13, 256-267. doi: 10.4236/jbm.2025.132020 .