Mitogen-Activated Protein Kinase (MAPK) signaling pathways play a crucial role in various cellular processes, including growth, differentiation, and response to stress. These pathways are ...

Mitogen-activated protein kinases (MAPKs) in tomato plants have crucial functions of mediating responses to environmental cues, internal signals, defense mechanisms, cellular processes, and plant ...

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...

One of the best studied signalling routes is the mitogen activated protein (MAP) kinase signal transduction pathway which plays a crucial role in many aspects of immune mediated inflammatory responses ...

MAP2K1 mutations have been functionally classified into three groups according to their dependency on upstream RAS/RAF signaling. However, the clinical efficacy of mitogen-activated protein kinase ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a ...

According to a new study published in the journal Cellular Signalling, cannabinoids may play a crucial role in preventing and treating brain diseases by regulating key physiological processes in the ...

The US Food and Drug Administration has approved mirdametinib for the treatment of neurofibromatosis type 1 (NF1) in adults ...

Its effect on cancer growth will take some explanation. An important cellular pathway is the mitogen-activated protein kinase (MAPK) pathway, which plays a critical role in integrating external ...

The table below is a review of notable updates that occurred in January 2025 for investigational products in development (not an inclusive list). Click on the status to view our full coverage.