In this important manuscript, the authors provide evidence for this mechanism in two different mechanically gated channels. The experiments were carried out in the same membranes, but the evidence is ...

Meeting is thrilled to announce that Morten Meldal, Nobel Laureate and Professor of Chemistry at the University of Copenhagen ...

The Nobel prizewinner used quantum and molecular mechanics to model the dynamics of complex chemical systems.

Molecular dynamics ... of how the molecules will interact – a force field – and are popular in materials chemistry, biochemistry and biophysics. Enhanced sampling simulations require ...

Integral membrane proteins carry out essential functions in the cell, and their activities are often modulated by specific protein-lipid interactions in the membrane. Here, we elucidate the intricate ...

Central European Institute of Technology, Masaryk University, Kamenice 5, CZ-62500 Brno, Czech Republic National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Kamenice 5, ...

Martin Karplus ’51 developed ground-breaking computer models to study chemical reactions and molecular dynamics, mentored ...

Build an empire, pilot a jumbo jet, or try your hand at industrial power-washing with these engrossing sim and sandbox games. My career has taken me through an eclectic assortment of fields, and ...

BEIJING, China I January 8, 2025 I In a recent achievement, DP Technology's hit discovery platform RiDYMO® has successfully designed a cyclic peptide ...

In a recent achievement, DP Technology's hit discovery platform RiDYMO® has successfully designed a cyclic peptide targeting ?-catenin, a historically "undruggable" protein, in just two months. This ...

Additionally, the peptide’s inherent modularity makes it a subject of interest for designing molecules tailored to interact with specific biological ... from molecular biology and immunology to ...

RiDYMO® has been successfully employed in various drug discovery programs, including the development of small molecule compounds for crucial targets such as c-Myc and GPX4, as well as other modalities ...