Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Opinion: Trump’s Gaza nonsense — Crazy scheme harms real steps for Mideast peace February 9, 2025 at 12:00 p.m. by The New York Daily News Editorial Board (TNS) ...

Gene sequencing of these D1.1 viruses has found a mutation that helps the virus copy itself more efficiently into the cells of mammals, including people. This change hasn’t been seen in other D1 ...

What do we love most about sci-fi horror? The tragic creatures caused by science gone wrong or the running and screaming from people in peril?

Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...

as well as by many AI companies — was largely nonsense. It was never going to be possible to contain the spread of this powerful emergent technology, and certainly not just by placing trade ...

We acknowledge Aboriginal and Torres Strait Islander peoples as the First Australians and Traditional Custodians of the lands where we live, learn and work.

The most common type of amino acid change identified in this study was frameshifts (17 variants, 50.00%), followed by nonsense (11 variants, 32.35%), InframeInsertion (three variants, 8.82%), missense ...

While some mutations can introduce premature termination codons (PTCs) into genes, nonsense mediated decay (NMD) can detect these PTCs and then eliminate the abnormal transcripts. PTCs and NMD play ...

Objectives Mutations in the X-linked endosomal Na+/H+ exchanger 6 (NHE6) cause Christianson syndrome (CS). Here, in the largest study to date, we examine genetic diversity and clinical progression in ...

While calling on Atiku and Wike to stop ‘this nonsense’, he enjoined the party to look inward and stop blaming the ruling All Progressives Congress for the crisis. “Throwing tantrums and ...