However, while the formation a ternary complex is crucial, it may not always guarantee successful protein degradation. The dynamics of the PROTAC-induced degradation complex play a key role in ...

People with diabetes should eat as much protein as people who don't have diabetes. In a healthy diet, roughly 10% to 35% of your daily calories should come from protein. Protein itself does not have ...

A concise overview of the ubiquitination pathway. Initially, the ubiquitin-activating enzyme E1 uses ATP hydrolysis energy to form a high-energy thioester bond between its cysteine residue (Cys) and ...