Diabetes can wreak havoc on the vasculature, leading to renal failure, blindness and cardiovascular disease. Such conditions are ultimately the result of reduced insulin production or insulin ...

The Bristol research initially focused on revealing underlying molecular mechanisms based on the glomerular podocyte, the central cell of the kidney filtration barrier. In 2002, the team led by ...

End-stage renal disease (ESRD) is defined as severe irreversible kidney damage, measured by the level of proteinuria and a reduction in the glomerular filtration rate to ˂15 ml/min/1.73 m2 ...

Steroid-resistant nephrotic syndrome (SRNS) is a devastating disease affecting both adults and children resulting from the breakdown of the kidney filtration barrier. It usually leads to end-stage ...

Nakamura says, "During our analysis of renal gene expression profiles using ... therapeutic breakthroughs in treating ...