Inhibition of nonsense-mediated decay turns immunologically cold tumors hot by increasing the amount of mutant RNA leading to an increase in T-cell-targetable neoantigens on the cell surface.

Protein phosphorylation is a cornerstone of cellular communication, orchestrating rapid and precise responses to ...

CIRBP Family, Tumors, Molecular Mechanisms, RNA-Binding Proteins, Cellular Stress Share and Cite: Cai, Y. , Wang, T. and Zhan ...

Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

Besides this, there are emerging findings that myeloid cells could be involved in tumor angiogenesis. In this article, we address the role of tyrosine kinase inhibitors in tumor immunology by ...

HMGA proteins have a crucial role in cell transformation ... mitogenic pressure and the inability to proceed through the cell cycle 21. The different cellular context might account for the ...

The immune system is made up of many interdependent parts, including lymphoid organs, cells, and cytokines, which play important roles in identifying, repelling, and eliminating pathogens and other ...

Both of ACE2 and transmembrane serine protease 2 (TMPRSS2) are key proteins of severe acute respiratory syndrome coronavirus (SARS ... After removing unwanted sources of variation, such as cell cycle ...

A "pocket" on the protein ... cell division when the pocket loses its shape and can no longer dock onto the substrate." The reason for this lies in the cyclins' cooperation with a kinase.

SIRT6, which belongs to the sirtuin family of NAD + -dependent deacetylases, has emerged as an important player in encouraging cancer cells to survive under oxidative stress, confirming its role in ..

A research team revealed that insulin-like growth factor-binding protein 6 (IGFBP6 ... IGFBP6 is known to play a crucial role in regulating cell cycle, proliferation, migration.