Scientists at the Wellcome Sanger Institute uncovered DNA damage that can persist for years, evading repair mechanisms and increasing mutation risks. This phenomenon provides new insights into cancer ...

New research shows persistent DNA lesions in stem cells contribute to mutations, with links to blood cancers and external ...

In a groundbreaking shift in our understanding of mutations, researchers have discovered types of DNA damage in healthy cells ...

The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...

STEM Potential supports you through years 10 and 12 with insightful lectures, subject-specific workshops and a non-residential summer school. STEM Potential is a multi-year programme of activities and ...

Pluripotent stem cells are cells that have the capacity to ... report a single-SALL4-mediated somatic reprogramming method and reveal the underlying mechanism of this process.

You began when egg and sperm met, and the DNA from your biological parents teamed up. Your first cell began copying its newly ...

Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Regenerative medicine has significantly impacted orthopaedic surgery by introducing biological therapies aimed at repairing, ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade ...