The chromosomal abnormalities included three unbalanced translocations, one interstitial duplication, and one interstitial deletion. The genetic abnormalities were predominantly identified in ...

All array platforms will detect copy number variations including deletions, duplications, unbalanced translocations, some marker chromosomes and aneuploidy. SNP arrays have the added advantage of ...

Purpose: To address some of the challenges facing the incorporation of array comparative genomic hybridization technology as a clinical tool, including archived tumor tissue, tumor heterogeneity ...

Molecular analysis through PCR unveiled the presence of BCR::ABL1mRNA with an e13/e14-a2 transcript, producing a p210 kD protein. Chromosome analysis identified unbalanced translocations involving ...

Genomic instability and amplification are intrinsically important traits determining the development and heterogeneity of tumors. The role of extrachromosomal circular DNA (eccDNA) in tumors has ...

Tom Stoppard wrote in The Real Thing, his enticing play about infidelity: “To marry one actress is unfortunate. To marry two is simply asking for it.” Here’s a political corollary: to elect ...

Our patient’s mother was a 24-year-old woman from Nicaragua, with no relevant medical history. Pregnancy was uncontrolled until 32 weeks gestation. An ultrasound study was performed in other ...

Either FISH or karyotyping is usually performed with CMA to confirm results and to identify translocations and insertions (46). While microarrays identify changes at specific regions of the genome, ...

This enables an unbiased assessment of genome-wide complex rearrangements and different classes of SVs (inversions, translocations, insertions, deletions, duplications) down to 500 base pairs (bp) in ...

Ms Chester’s comments, and the broader report, drew the ire of Australian Chamber of Commerce and Industry chief executive Andrew McKellar, who said the report's recommendations were unbalanced and ...